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The antibody against Minpp1 was raised in rabbit using the Recombinant Rat Multiple inositol polyphosphate phosphatase 1 protein (31-481AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against Minpp1 was raised in rabbit using the Recombinant Rat Multiple inositol polyphosphate phosphatase 1 protein (31-481AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-43965A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MINPP1 |
| Target Synonyms | 3, 3-bisphosphoglycerate 3-phosphatase antibody; 2, 3-BPG phosphatase antibody; EC 3.1.3.80 antibody; Inositol antibody; 1, 4, 5)-tetrakisphosphate 3-phosphatase antibody; Ins(1, 5)P(4) 3-phosphatase antibody, Minpp1 antibody; Mipp1 antibody; Multiple inositol polyphosphate phosphatase 1 antibody; EC 3.1.3.62 antibody; 2 | Form | Liquid |
| Species Reactivity | Rat | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Rat Multiple inositol polyphosphate phosphatase 1 protein (31-481AA) | Target Species | Rattus norvegicus (Rat) |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O35217 |
Uniprot Id
O35217
Target Species
Rat
Target Name
MINPP1
Target Full Name
Multiple inositol polyphosphate phosphatase 1
Target Function
Acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). Also acts as a 2,3-bisphosphoglycerate 3-phosphatase, by mediating the dephosphorylation of 2,3-bisphosphoglycerate (2,3-BPG) to produce phospho-D-glycerate without formation of 3-phosphoglycerate. May play a role in bone development (endochondral ossification). May play a role in the transition of chondrocytes from proliferation to hypertrophy.
Target Subcellular Location
Endoplasmic reticulum lumen.
Target Protein Families
Histidine acid phosphatase family, MINPP1 subfamily
Target Tissue Specificity
Widely expressed with highest levels in kidney and liver. Expressed in chondrocytes with an elevated expression in hypertrophic chondrocytes.
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