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The antibody against sspB was raised in rabbit using the Recombinant Staphylococcus aureus Staphopain B protein (220-393AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against sspB was raised in rabbit using the Recombinant Staphylococcus aureus Staphopain B protein (220-393AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-50114A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | sspB |
| Target Synonyms | sspB antibody; SAV1047 antibody; Staphopain B antibody; EC 3.4.22.- antibody; Staphylococcal cysteine proteinase B antibody; Staphylopain B antibody | Form | Liquid |
| Species Reactivity | Staphylococcus aureus | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Staphylococcus aureus Staphopain B protein (220-393AA) | Target Species | Staphylococcus aureus (strain Mu50 / ATCC 700699) |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q99V46 |
Uniprot Id
Q99V46
Target Species
Staphylococcus aureus
Target Name
SSPB
Target Function
Cysteine protease that plays an important role in the inhibition of host innate immune response. Degrades host elastin, fibrogen, fibronectin and kininogen. Blocks phagocytosis of opsonised S. aureus by neutrophils and monocytes by inducing their death in a proteolytic activity-dependent manner. Decreases surface expression of the 'don't eat me' signal CD31 on neutrophils. Cleaves host galectin-3/LGALS3, thereby inhibiting the neutrophil-activating ability of the lectin.
Target Subcellular Location
Secreted.
Target Protein Families
Peptidase C47 family
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