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The antibody against cyp26a1 was raised in rabbit using the Recombinant Zebrafish Cytochrome P450 26A1 protein (244-371AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
The antibody against cyp26a1 was raised in rabbit using the Recombinant Zebrafish Cytochrome P450 26A1 protein (244-371AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
$299.00
Western Blot_x000D_ | Positive WB detected in: Zebrafish tissue, Zebrafish eye tissue_x000D_ | All lanes: cyp26a1 at 1:2000_x000D_ | Secondary_x000D_ | Goat polyclonal to rabbit IgG at 1/50000 dilution_x000D_ | Predicted band size: 57 kDa_x000D_ | Observed band size: 57 kDa
| Cat.No | ADC-04372A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | cyp26a1 |
| Target Synonyms | cyp26a1 antibody; cyp26Cytochrome P450 26A1 antibody; EC 1.14.13.- antibody; Cytochrome P450RAI antibody; Retinoic acid 4-hydroxylase antibody; Retinoic acid-metabolizing cytochrome antibody | Form | Liquid |
| Species Reactivity | Zebrafish | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Zebrafish Cytochrome P450 26A1 protein (244-371AA) | Target Species | Zebrafish |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P79739 |
Uniprot Id
P79739
Target Species
Zebrafish
Target Name
CYP26A1
Target Function
A cytochrome P450 monooxygenase involved in the metabolism of all-trans retinoic acid (atRA), a signaling molecule that binds to retinoic acid receptors and regulates gene transcription. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon hydrogen bonds of atRA primarily at C-4. Has no activity toward 9-cis and 13-cis retinoic acid stereoisomers. May play a role in the oxidative metabolism of xenobiotics such as tazarotenic acid.
Target Subcellular Location
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Target Protein Families
Cytochrome P450 family
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