Mediator Of Rna Polymerase Ii Transcription Subunit 12-Like Protein (MED12L) Reagents

Mediator of RNA polymerase II transcription subunit 12-like protein

May be a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Nucleus.

Mediator complex subunit 12 family

MED12L; KIAA1635; TNRC11L; TRALP; TRALPUSH; PRO0314; Mediator of RNA polymerase II transcription subunit 12-like protein; Mediator complex subunit 12-like protein; Thyroid hormone receptor-associated-like protein; Trinucleotide repeat-containing gene 11 protein-like