Polypyrimidine Tract-Binding Protein 3 (PTBP3) Reagents

Polypyrimidine tract-binding protein 3

RNA-binding protein that mediates pre-mRNA alternative splicing regulation. Plays a role in the regulation of cell proliferation, differentiation and migration. Positive regulator of EPO-dependent erythropoiesis. Participates in cell differentiation regulation by repressing tissue-specific exons. Promotes FAS exon 6 skipping. Binds RNA, preferentially to both poly(G) and poly(U).

Expressed in several hematopoietic cell lines examined.

DKFZp781I1117; Fission yeast differentiation regulator; OTTHUMP00000021931; OTTHUMP00000021932; Polypyrimidine tract binding protein 3; regulator of differentiation 1; Regulator of differentiation (in S. pombe) 1; Regulator of differentiation 1; ROD 1; Rod1; ROD1 regulator of differentiation 1; ROD1_HUMAN