Soluble Scavenger Receptor Cysteine-Rich Domain-Containing Protein Ssc5D (SSC5D) Reagents

Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D

Binds to extracellular matrix proteins. Binds to pathogen-associated molecular patterns (PAMPs) present on the cell walls of Gram-positive and Gram-negative bacteria and fungi, behaving as a pattern recognition receptor (PRR). Induces bacterial and fungal aggregation and subsequent inhibition of PAMP-induced cytokine release. Does not possess intrinsic bactericidal activity. May play a role in the innate defense and homeostasis of certain epithelial surfaces.

Secreted. Cytoplasm.

Highly expressed in monocytes/macrophages and T-lymphocytes. Highly expressed in placenta and spleen, and also detected at lower levels in colon, and more weakly in lung, heart and kidney.

SSC5DSoluble scavenger receptor cysteine-rich domain-containing protein SSC5D; Soluble scavenger protein with 5 SRCR domains; SSc5D