Rabbit anti-Human WNT2 Polyclonal Antibody

The antibody against WNT2 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human WNT2 (NP_003382.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

ADA-11463A

Number

Cat.No	ADA-11463A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	WNT2
Target Synonyms	IRP; INT1L1; WNT2	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	Mouse liver, Rat liver	Application	ELISA, WB, IF/ICC

Cat.No

ADA-11463A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

WNT2

Target Synonyms

IRP; INT1L1; WNT2

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

Mouse liver, Rat liver

Application

ELISA, WB, IF/ICC

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human WNT2 (NP_003382.1).	Target Species	Human
Immunogen Sequence	MNAPLGGIWLWLPLLLTWLTPEVNSSWWYMRATGGSSRVMCDNVPGLVSSQRQLCHRHPDVMRAISQGVAEWTAECQHQFRQHRWNCNTLDRDHSLFGRV	Uniprot ID	P09544

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human WNT2 (NP_003382.1).

Target Species

Human

Immunogen Sequence

MNAPLGGIWLWLPLLLTWLTPEVNSSWWYMRATGGSSRVMCDNVPGLVSSQRQLCHRHPDVMRAISQGVAEWTAECQHQFRQHRWNCNTLDRDHSLFGRV

Uniprot ID

P09544

Background Information

Uniprot Id

P09544
Target Species

Human
Target Name

WNT2
Target Full Name

Protein Wnt-2
Target Function

Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family. Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons.
Target Subcellular Location

Secreted, extracellular space, extracellular matrix. Secreted.
Target Protein Families

Wnt family
Target Tissue Specificity

Expressed in brain in the thalamus, in fetal and adult lung and in placenta.
Target Research Area

Cancer, Stem Cells
Target Synonyms

Int 1 related protein; Int-1-like protein 1; Int-1-related protein; INT1L 1; INT1L1; IRP; IRP protein; ONCOGENE INT1 LIKE 1; Protein Wnt-2; Secreted growth factor; Wingless type MMTV integration site family member 2; WNT 2; WNT2; WNT2_HUMAN
Target Background

This gene is a member of the WNT gene family. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Alternatively spliced transcript variants have been identified for this gene.

Rabbit anti-Human WNT2 Polyclonal Antibody

Specifications

Immunogen Information

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