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Rabbit anti-Human PXDN Polyclonal Antibody

The antibody against PXDN was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1320-1479 of human PXDN (NP_036425.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-12037A

The antibody against PXDN was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1320-1479 of human PXDN (NP_036425.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-12037A ClonalityPolyclonal
Host SpeciesRabbitTarget NamePXDN
Target SynonymsPXN; VPO; MG50; PRG2; ASGD7; COPOA; D2S448; D2S448E; hsPxd01; PXDNFormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse lung, RajiApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1320-1479 of human PXDN (NP_036425.1).Target SpeciesHuman
Immunogen SequenceRTRGQFNAFSYHFRGRRSLEFSYQEDKPTKKTRPRKIPSVGRQGEHLSNSTSAFSTRSDASGTNDFREFVLEMQKTITDLRTQIKKLESRLSTTECVDAGGESHANNTKWKKDACTICECKDGQVTCFVEACPPATCAVPVNIPGACCPVCLQKRAEEKPUniprot IDQ92626
Background Information
  • Uniprot Id

    Q92626

  • Target Species

    Human

  • Target Name

    PXDN

  • Target Full Name

    Peroxidasin homolog

  • Target Function

    Displays low peroxidase activity and is likely to participate in H(2)O(2) metabolism and peroxidative reactions in the cardiovascular system. Plays a role in extracellular matrix formation.

  • Target Involvement

    Anterior segment dysgenesis 7 (ASGD7)

  • Target Subcellular Location

    Secreted, extracellular space, extracellular matrix. Note=Enriched in the peritubular space of fibrotic kidneys.

  • Target Protein Families

    Peroxidase family, XPO subfamily

  • Target Tissue Specificity

    Expressed at higher levels in heart, lung, ovary, spleen, intestine and placenta, and at lower levels in liver, colon, pancreas, kidney, thymus, skeletal muscle and prostate. Expressed in tumors such as melanoma, breast cancer, ovarian cancer and glioblas

  • Target Synonyms

    PXDN; KIAA0230; MG50; PRG2; VPO; VPO1; Peroxidasin homolog; EC 1.11.1.7; Melanoma-associated antigen MG50; Vascular peroxidase 1; p53-responsive gene 2 protein

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