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The antibody against ADH1C was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-375 of human ADH1C (NP_000660.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against ADH1C was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-375 of human ADH1C (NP_000660.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-12298A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ADH1C |
| Target Synonyms | ADH3; ADH1C | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | 293T, A-549, HepG2 | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-375 of human ADH1C (NP_000660.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P00326 | Immunogen Sequence |
Uniprot Id
P00326
Target Species
Human
Target Name
ADH1C
Target Full Name
Alcohol dehydrogenase 1C
Target Subcellular Location
Cytoplasm.
Target Protein Families
Zinc-containing alcohol dehydrogenase family
Target Research Area
Signal Transduction
Target Synonyms
ADH gamma subunit; ADH1C; ADH1G_HUMAN; Adh3; Alcohol dehydrogenase 1C (class I) gamma polypeptide; Alcohol dehydrogenase 1C; Alcohol dehydrogenase 1C gamma polypeptide; Alcohol dehydrogenase 3 (class I) gamma polypeptide; Alcohol dehydrogenase 3; Alcohol dehydrogenase subunit gamma; Aldehyde reductase; Class I alcohol dehydrogenase; OTTHUMP00000220209
Target Background
This gene encodes class I alcohol dehydrogenase, gamma subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class I alcohol dehydrogenase, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation to acetaldehyde, thus playing a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. An association between ADH1C polymorphism and alcohol dependence has not been established.
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