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Rabbit anti-Human KCNQ3 Polyclonal Antibody

The antibody against KCNQ3 was raised in rabbit using the Recombinant Human Potassium voltage-gated channel subfamily KQT member 3 protein (763-872AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.

ADC-07933A

The antibody against KCNQ3 was raised in rabbit using the Recombinant Human Potassium voltage-gated channel subfamily KQT member 3 protein (763-872AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.

$299.00

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Specifications


Cat.No ADC-07933A ClonalityPolyclonal
Host SpeciesRabbitTarget NameKCNQ3
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, IF, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Potassium voltage-gated channel subfamily KQT member 3 protein (763-872AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDO43525
Background Information
  • Uniprot Id

    O43525

  • Target Species

    Human

  • Target Name

    KCNQ3

  • Target Full Name

    Potassium voltage-gated channel subfamily KQT member 3

  • Target Function

    Associates with KCNQ2 or KCNQ5 to form a potassium channel with essentially identical properties to the channel underlying the native M-current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons as well as the responsiveness to synaptic inputs. Therefore, it is important in the regulation of neuronal excitability.

  • Target Involvement

    Seizures, benign familial neonatal 2 (BFNS2)

  • Target Subcellular Location

    Cell membrane; Multi-pass membrane protein.

  • Target Protein Families

    Potassium channel family, KQT (TC 1.A.1.15) subfamily, Kv7.3/KCNQ3 sub-subfamily

  • Target Tissue Specificity

    Predominantly expressed in brain.

  • Target Synonyms

    BFNC 2; BFNC; BFNC2; EBN 2; EBN2; KCNQ 3; KCNQ3; KCNQ3_HUMAN; KQT like 3; KQT-like 3; KV7.3; Potassium channel subunit alpha KvLQT3; Potassium channel voltage gated subfamily Q member 3; Potassium voltage gated channel KQT like protein 3; Potassium voltage gated channel KQT like subfamily member 3; Potassium voltage gated channel subfamily KQT member 3; Potassium voltage-gated channel subfamily KQT member 3; Voltage gated potassium channel subunit Kv7.3; Voltage-gated potassium channel subunit Kv7.3

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