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The antibody against IRX3 was raised in rabbit using the Recombinant Human Iroquois-class homeodomain protein IRX-3 protein (285-378AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
The antibody against IRX3 was raised in rabbit using the Recombinant Human Iroquois-class homeodomain protein IRX-3 protein (285-378AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
$299.00
| Cat.No | ADC-07950A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | IRX3 |
| Form | Liquid | Species Reactivity | Human, Rat |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Iroquois-class homeodomain protein IRX-3 protein (285-378AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P78415 |
Uniprot Id
P78415
Target Species
Human
Target Name
IRX3
Target Full Name
Iroquois-class homeodomain protein IRX-3
Target Function
Transcription factor involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells. Acts as a regulator of energy metabolism.
Target Subcellular Location
Nucleus.
Target Protein Families
TALE/IRO homeobox family
Target Synonyms
AI894186; Homeodomain protein IRXB1; Iroquois class homeodomain protein IRX 1; Iroquois homeobox 3; Iroquois homeobox protein 3; Iroquois-class homeodomain protein irx-3; IRX 1; irx3; IRX3_HUMAN; IRXB1
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