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Rabbit anti-Human FSHR Polyclonal Antibody

The antibody against FSHR was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 631-695 of human FSHR (NP_000136.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-12764A

The antibody against FSHR was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 631-695 of human FSHR (NP_000136.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-12764A ClonalityPolyclonal
Host SpeciesRabbitTarget NameFSHR
Target SynonymsLGR1; ODG1; FSHR1; FSHRO; FSHRFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse liverApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 631-695 of human FSHR (NP_000136.2).Target SpeciesHuman
Immunogen SequenceKNFRRDFFILLSKCGCYEMQAQIYRTETSSTVHNTHPRNGHCSSAPRVTSGSTYILVPLSHLAQNUniprot IDP23945
Background Information
  • Uniprot Id

    P23945

  • Target Species

    Human

  • Target Name

    FSHR

  • Target Full Name

    Follicle-stimulating hormone receptor

  • Target Function

    G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.

  • Target Involvement

    Ovarian dysgenesis 1 (ODG1); Ovarian hyperstimulation syndrome (OHSS)

  • Target Subcellular Location

    Cell membrane; Multi-pass membrane protein.

  • Target Protein Families

    G-protein coupled receptor 1 family, FSH/LSH/TSH subfamily

  • Target Tissue Specificity

    Sertoli cells and ovarian granulosa cells.

  • Target Research Area

    G-protein coupled receptor, Neuroscience

  • Target Synonyms

    Follicle stimulating hormone receptor; Follicle stimulating hormone receptor isoform 1; Follicle-stimulating hormone receptor; Follitropin receptor; FSH receptor; FSH-R; Fshr; FSHR_HUMAN; FSHRO; LGR1; MGC141667; MGC141668; ODG1; ovarian dysgenesis 1

  • Target Background

    The protein encoded by this gene belongs to family 1 of G-protein coupled receptors. It is the receptor for follicle stimulating hormone and functions in gonad development. Mutations in this gene cause ovarian dysgenesis type 1, and also ovarian hyperstimulation syndrome. Alternative splicing results in multiple transcript variants.

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