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The antibody against Nestin was raised in Rabbit using the recombinant Protein corresponding to a sequence within amino acids 1392-1621 of human NES (NP_006608.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
The antibody against Nestin was raised in Rabbit using the recombinant Protein corresponding to a sequence within amino acids 1392-1621 of human NES (NP_006608.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
| Cat.No | ADA-12919A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | Nestin |
| Target Synonyms | Nbla00170; Nestin | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Neuro-2a | Application | ELISA, WB, IF/ICC, IHC-P |
| Immunogen Description | Recombinant Protein corresponding to a sequence within amino acids 1392-1621 of human NES (NP_006608.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P48681 | Immunogen Sequence |
Uniprot Id
P48681
Target Species
Human
Target Name
NES
Target Full Name
Nestin
Target Function
Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells.
Target Protein Families
Intermediate filament family
Target Tissue Specificity
CNS stem cells.
Target Research Area
Neuroscience
Target Synonyms
ESTM 46; FLJ 21841; FLJ21841; Intermediate filament protein; Nbla00170; nes; NEST_HUMAN; Nestin
Target Background
This gene encodes a member of the intermediate filament protein family and is expressed primarily in nerve cells.
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