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Rabbit anti-Human MDH2 Monoclonal Antibody

The antibody against MDH2 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 50-150 of human MDH2 (P40926) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

ADA-13182A

The antibody against MDH2 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 50-150 of human MDH2 (P40926) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

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Specifications


Cat.No ADA-13182A ClonalityMonoclonal
Host SpeciesRabbitTarget NameMDH2
Target SynonymsMDH; MOR1; DEE51; M-MDH; EIEE51; MGC:3559; MDH2FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLa, NIH/3T3, A-431, Mouse small intestine, Rat kidney, U-87MGApplicationELISA, WB, IHC-P

Immunogen Information


Immunogen DescriptionA synthetic peptide corresponding to a sequence within amino acids 50-150 of human MDH2 (P40926).Target SpeciesHuman
Immunogen SequenceVSRLTLYDIAHTPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMICVIANPVNSTIPIUniprot IDP40926
Background Information
  • Uniprot Id

    P40926

  • Target Species

    Human

  • Target Name

    MDH2

  • Target Full Name

    Malate dehydrogenase, mitochondrial

  • Target Involvement

    Epileptic encephalopathy, early infantile, 51 (EIEE51)

  • Target Subcellular Location

    Mitochondrion matrix.

  • Target Protein Families

    LDH/MDH superfamily, MDH type 1 family

  • Target Research Area

    Signal Transduction

  • Target Synonyms

    M MDH; Malate dehydrogenase 2; NAD (mitochondrial); Malate dehydrogenase; Malate dehydrogenase; mitochondrial; MDH; mdh2; MDHM_HUMAN; MGC:3559; mitochondrial; Mitochondrial malate dehydrogenase 2; NAD; Mor 1; MOR1

  • Target Background

    Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the mitochondria and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Several transcript variants encoding different isoforms have been found for this gene.

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