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Rabbit anti-Human ERp19 Monoclonal Antibody

The antibody against ERp19 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human ERp19 (NP_056997.1) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

ADA-13446A

The antibody against ERp19 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human ERp19 (NP_056997.1) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

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Specifications


Cat.No ADA-13446A ClonalityMonoclonal
Host SpeciesRabbitTarget NameERp19
Target SynonymsAG1; AGR1; ERP16; ERP18; ERP19; TLP19; hAG-1; PDIA16; hTLP19; ERp19FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesRat heart, 293T, HT-29, Rat kidney, Rat lung, SH-SY5YApplicationELISA, WB, IHC-P

Immunogen Information


Immunogen DescriptionA synthetic peptide corresponding to a sequence within amino acids 1-100 of human ERp19 (NP_056997.1).Target SpeciesHuman
Immunogen SequenceMETRPRLGATCLLGFSFLLLVISSDGHNGLGKGFGDHIHWRTLEDGKKEAAASGLPLMVIIHKSWCGACKALKPKFAESTEISELSHNFVMVNLEDEEEPUniprot IDO95881
Background Information
  • Uniprot Id

    O95881

  • Target Species

    Human

  • Target Name

    TXNDC12

  • Target Full Name

    Thioredoxin domain-containing protein 12

  • Target Function

    Possesses significant protein thiol-disulfide oxidase activity.

  • Target Subcellular Location

    Endoplasmic reticulum lumen.

  • Target Tissue Specificity

    Widely expressed.

  • Target Research Area

    Signal Transduction

  • Target Synonyms

    AG1; AGR1; anterior gradient homolog 1; endoplasmic reticulum protein ERp19; Endoplasmic reticulum resident protein 18; Endoplasmic reticulum resident protein 19; endoplasmic reticulum thioredoxin superfamily member, 18 kDa; ER protein 18; ER protein 19; ERP 18; ERP16; ERp18; ERp19; hAG 1; hAG1; hTLP19; PDIA16; protein disulfide isomerase family A, member 16; thioredoxin domain containing 12 (endoplasmic reticulum; Thioredoxin domain-containing protein 12; thioredoxin like protein p19; Thioredoxin-like protein p19; TLP19; TXD12_HUMAN; TXNDC12

  • Target Background

    This gene encodes a member of the thioredoxin superfamily. Members of this family are characterized by a conserved active motif called the thioredoxin fold that catalyzes disulfide bond formation and isomerization. This protein localizes to the endoplasmic reticulum and has a single atypical active motif. The encoded protein is mainly involved in catalyzing native disulfide bond formation and displays activity similar to protein-disulfide isomerases. This protein may play a role in defense against endoplasmic reticulum stress. Alternate splicing results in both coding and non-coding variants.

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