Rabbit anti-Human MAD2L1BP Monoclonal Antibody

The antibody against MAD2L1BP was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 175-274 of human MAD2L1BP (Q15013) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

ADA-13447A

Number

Cat.No	ADA-13447A	Clonality	Monoclonal
Host Species	Rabbit	Target Name	MAD2L1BP
Target Synonyms	CMT2; MAD2L1BP	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	HeLa, HepG2	Application	ELISA, WB, IHC-P

Cat.No

ADA-13447A

Clonality

Monoclonal

Host Species

Rabbit

Target Name

MAD2L1BP

Target Synonyms

CMT2; MAD2L1BP

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

HeLa, HepG2

Application

ELISA, WB, IHC-P

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 175-274 of human MAD2L1BP (Q15013).	Target Species	Human
Immunogen Sequence	YSVDQSLSTAACLRRLFRAIFMADAFSELQAPPLMGTVVMAQGHRNCGEDWFRPKLNYRVPSRGHKLTVTLSCGRPSIRTTAWEDYIWFQAPVTFKGFRE	Uniprot ID	Q15013

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 175-274 of human MAD2L1BP (Q15013).

Target Species

Human

Immunogen Sequence

YSVDQSLSTAACLRRLFRAIFMADAFSELQAPPLMGTVVMAQGHRNCGEDWFRPKLNYRVPSRGHKLTVTLSCGRPSIRTTAWEDYIWFQAPVTFKGFRE

Uniprot ID

Q15013

Background Information

Uniprot Id

Q15013
Target Species

Human
Target Name

MAD2L1BP
Target Full Name

MAD2L1-binding protein
Target Function

May function to silence the spindle checkpoint and allow mitosis to proceed through anaphase by binding MAD2L1 after it has become dissociated from the MAD2L1-CDC20 complex.
Target Subcellular Location

Nucleus. Cytoplasm, cytoskeleton, spindle. Note=During early mitosis, unevenly distributed throughout the nucleoplasm. From metaphase to anaphase, concentrated on the spindle.
Target Protein Families

MAD2L1BP family
Target Synonyms

Caught by MAD2 protein; CMT2; dJ261G23.1 ; KIAA0110; MAD2L1 binding protein; MAD2L1 binding protein isoform 2; MAD2L1-binding protein; Mad2l1bp; MD2BP_HUMAN; MGC11282; OTTHUMP00000016496; RP1 261G23.6
Target Background

The protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1). MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Rabbit anti-Human MAD2L1BP Monoclonal Antibody

Specifications

Immunogen Information

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