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Rabbit anti-Human NQO2 Monoclonal Antibody

The antibody against NQO2 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human NQO2 (P16083) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-13806A

The antibody against NQO2 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human NQO2 (P16083) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-13806A ClonalityMonoclonal
Host SpeciesRabbitTarget NameNQO2
Target SynonymsQR2; DHQV; DIA6; NMOR2; NQO2FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse kidney, Mouse liver, Mouse thymus, Rat kidneyApplicationELISA, WB

Immunogen Information


Immunogen DescriptionA synthetic peptide corresponding to a sequence within amino acids 1-100 of human NQO2 (P16083).Target SpeciesHuman
Immunogen SequenceMAGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNLEPRATDKDITGTLSNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFUniprot IDP16083
Background Information
  • Uniprot Id

    P16083

  • Target Species

    Human

  • Target Name

    NQO2

  • Target Full Name

    Ribosyldihydronicotinamide dehydrogenase [quinone]

  • Target Function

    The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.

  • Target Subcellular Location

    Cytoplasm.

  • Target Protein Families

    NAD(P)H dehydrogenase (quinone) family

  • Target Synonyms

    DHQV; DIA6; EC 1.10.99.2; MGC94180; NAD(P)H dehydrogenase quinone 2; NAD(P)H menadione oxidoreductase 1 dioxin inducible 2; NAD(P)H menadione oxidoreductase 2 dioxin inducible ; NMOR2; NQO 2; NQO2; NQO2_HUMAN; NRH dehydrogenase [quinone] 2; NRH dehydrogenase; NRH:quinone oxidoreductase 2; OTTHUMP00000015948; OTTHUMP00000015949; OTTHUMP00000015953; Ox 2; Ox2; QR2; Quinone; Quinone reductase 2; Ribosyldihydronicotinamide dehydrogenase [quinone]; Ribosyldihydronicotinamide dehydrogenase

  • Target Background

    This gene encodes a member of the thioredoxin family of enzymes. It is a cytosolic and ubiquitously expressed flavoprotein that catalyzes the two-electron reduction of quinone substrates and uses dihydronicotinamide riboside as a reducing coenzyme. Mutations in this gene have been associated with neurodegenerative diseases and several cancers. Alternative splicing results in multiple transcript variants.

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