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The antibody against BDKRB2 was raised in rabbit using the Recombinant Human B2 bradykinin receptor protein (336-391AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.
The antibody against BDKRB2 was raised in rabbit using the Recombinant Human B2 bradykinin receptor protein (336-391AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.
$299.00
Western Blot | Positive WB detected in: A549 whole cell lysate, MCF-7 whole cell lysate, Hela whole cell lysate | All lanes: BDKRB2 antibody at 1:2000 | Secondary | Goat polyclonal to rabbit IgG at 1/50000 dilution | Predicted band size: 45, 42 kDa | Observed band size: 55 kDa
| Cat.No | ADC-08061A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | BDKRB2 |
| Target Synonyms | BDKRB2; BKR2; B2 bradykinin receptor; B2R; BK-2 receptor | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human B2 bradykinin receptor protein (336-391AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P30411 |
Uniprot Id
P30411
Target Species
Human
Target Name
BDKRB2
Target Full Name
B2 bradykinin receptor
Target Function
Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
G-protein coupled receptor 1 family, Bradykinin receptor subfamily, BDKRB2 sub-subfamily
Target Tissue Specificity
Ubiquitous. Widespread in normal smooth muscle tissue and neurons.
Target Synonyms
BDKRB2; BKR2; B2 bradykinin receptor; B2R; BK-2 receptor
Target Background
This gene encodes a receptor for bradykinin. The 9 aa bradykinin peptide elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. Bradykinin is released upon activation by pathophysiologic conditions such as trauma and inflammation, and binds to its kinin receptors, B1 and B2. The B2 receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system.
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