Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against TLE2 was raised in Rabbit using the recombinant protein of human TLE2 as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against TLE2 was raised in Rabbit using the recombinant protein of human TLE2 as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-15325A | Clonality | Monoclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TLE2 |
| Target Synonyms | ESG; ESG2; GRG2; TLE2 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, 0.05% BSA, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | K-562, MCF7, SH-SY5Y | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant protein of human TLE2. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q04725 |
Uniprot Id
Q04725
Target Species
Human
Target Name
TLE2
Target Full Name
Transducin-like enhancer protein 2
Target Function
Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.
Target Subcellular Location
Nucleus.
Target Protein Families
WD repeat Groucho/TLE family
Target Tissue Specificity
In all tissues examined, mostly in heart, brain, and muscle.
Target Synonyms
ESG; ESG2; GRG2; TLE2
Target Background
Enables transcription corepressor activity. Involved in negative regulation of canonical Wnt signaling pathway and negative regulation of transcription, DNA-templated. Located in focal adhesion and nuclear body.
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
