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Rabbit anti-Human Calponin Monoclonal Antibody

The antibody against Calponin was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 198-297 of human Calponin (P51911) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.

ADA-16948A

The antibody against Calponin was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 198-297 of human Calponin (P51911) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.

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Specifications


Cat.No ADA-16948A ClonalityMonoclonal
Host SpeciesRabbitTarget NameCalponin
Target SynonymsSMCC; Sm-Calp; HEL-S-14; CalponinFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse heart, Mouse kidney, Mouse lung, Rat lung, Rat uterusApplicationELISA, WB, IF/ICC, IHC-P

Immunogen Information


Immunogen DescriptionA synthetic peptide corresponding to a sequence within amino acids 198-297 of human Calponin (P51911).Target SpeciesHuman
Immunogen SequencePLDQATISLQMGTNKGASQAGMTAPGTKRQIFEPGLGMEHCDTLNVSLQMGSNKGASQRGMTVYGLPRQVYDPKYCLTPEYPELGEPAHNHHAHNYYNSAUniprot IDP51911
Background Information
  • Uniprot Id

    P51911

  • Target Species

    Human

  • Target Name

    CNN1

  • Target Full Name

    Calponin-1

  • Target Function

    Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

  • Target Protein Families

    Calponin family

  • Target Tissue Specificity

    Smooth muscle, and tissues containing significant amounts of smooth muscle.

  • Target Research Area

    Cardiovascular

  • Target Synonyms

    Basic calponin; Calponin 1; Calponin 1 basic smooth muscle; Calponin H1; Calponin H1 smooth muscle; Calponin-1; Calponin1; Calponins basic; CNN 1; Cnn1; CNN1_HUMAN; Epididymis secretory protein Li 14; HEL S 14; Sm Calp; SMCC; smooth muscle

  • Target Background

    Predicted to enable actin binding activity. Involved in negative regulation of vascular associated smooth muscle cell proliferation. Located in cytoskeleton.

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