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The antibody against Collagen X/COL10A1 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 500-600 of human Collagen X/COL10A1 (Q03692) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against Collagen X/COL10A1 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 500-600 of human Collagen X/COL10A1 (Q03692) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-16991A | Clonality | Monoclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | Collagen X/COL10A1 |
| Target Synonyms | COL10A1; collagen alpha-1(X) chain; Collagen X/COL10A1 | Form | Liquid |
| Species Reactivity | Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse liver, Rat liver | Application | ELISA, WB |
| Immunogen Description | A synthetic peptide corresponding to a sequence within amino acids 500-600 of human Collagen X/COL10A1 (Q03692). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | HSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTGMPVSAFTVILSKAYPAIGTPIPFDKILYNRQQHYDPRTGIFTCQIPGIYYFS | Uniprot ID | Q03692 |
Uniprot Id
Q03692
Target Species
Human
Target Name
COL10A1
Target Full Name
Collagen alpha-1(X) chain
Target Function
Type X collagen is a product of hypertrophic chondrocytes and has been localized to presumptive mineralization zones of hyaline cartilage.
Target Involvement
Schmid type metaphyseal chondrodysplasia (SMCD)
Target Subcellular Location
Secreted, extracellular space, extracellular matrix.
Target Synonyms
COL10A1; collagen alpha-1(X) chain
Target Background
This gene encodes the alpha chain of type X collagen, a short chain collagen expressed by hypertrophic chondrocytes during endochondral ossification. Unlike type VIII collagen, the other short chain collagen, type X collagen is a homotrimer. Mutations in this gene are associated with Schmid type metaphyseal chondrodysplasia (SMCD) and Japanese type spondylometaphyseal dysplasia (SMD).
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