Rabbit anti-Human MUC2 Monoclonal Antibody

The antibody against MUC2 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 5000-5100 of human MUC2 (Q02817) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

ADA-17014A

Number

Cat.No	ADA-17014A	Clonality	Monoclonal
Host Species	Rabbit	Target Name	MUC2
Target Synonyms	MLP; SMUC; MUC-2; MUC2	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	HeLa, Mouse stomach, Rat large intestine, SGC-7901	Application	ELISA, WB, IHC-P

Cat.No

ADA-17014A

Clonality

Monoclonal

Host Species

Rabbit

Target Name

MUC2

Target Synonyms

MLP; SMUC; MUC-2; MUC2

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

HeLa, Mouse stomach, Rat large intestine, SGC-7901

Application

ELISA, WB, IHC-P

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 5000-5100 of human MUC2 (Q02817).	Target Species	Human
Immunogen Sequence	PDNQHVILKPGDFKSDPKNNCTFFSCVKIHNQLISSVSNITCPNFDASICIPGSITFMPNGCCKTCTPRNETRVPCSTVPVTTEVSYAGCTKTVLMNHCSG	Uniprot ID	Q02817

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 5000-5100 of human MUC2 (Q02817).

Target Species

Human

Immunogen Sequence

PDNQHVILKPGDFKSDPKNNCTFFSCVKIHNQLISSVSNITCPNFDASICIPGSITFMPNGCCKTCTPRNETRVPCSTVPVTTEVSYAGCTKTVLMNHCSG

Uniprot ID

Q02817

Background Information

Uniprot Id

Q02817
Target Species

Human
Target Name

MUC2
Target Full Name

Mucin-2
Target Function

Coats the epithelia of the intestines, airways, and other mucus membrane-containing organs. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Major constituent of both the inner and outer mucus layers of the colon and may play a role in excluding bacteria from the inner mucus layer.
Target Subcellular Location

Secreted.
Target Tissue Specificity

Colon, small intestine, colonic tumors, bronchus, cervix and gall bladder.
Target Research Area

Signal Transduction
Target Synonyms

Intestinal mucin 2; Intestinal mucin-2; MLP; MUC 2; MUC-2; Muc2; MUC2_HUMAN; Mucin 2; Mucin 2 intestinal; Mucin 2 intestinal/tracheal; Mucin 2 oligomeric mucus/gel forming; Mucin 2 precursor ; Mucin 2 tracheal ; Mucin like protein; Mucin-2; Mucin2; SMUC
Target Background

This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. The protein polymerizes into a gel of which 80% is composed of oligosaccharide side chains by weight. The protein features a central domain containing tandem repeats rich in threonine and proline that varies between 50 and 115 copies in different individuals. Downregulation of this gene has been observed in patients with Crohn disease and ulcerative colitis.

Rabbit anti-Human MUC2 Monoclonal Antibody

Specifications

Immunogen Information

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