Rabbit anti-Human SOD2 Polyclonal Antibody

The antibody against SOD2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 25-222 of human SOD2 (NP_000627.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.

ADA-17151A

Number

Cat.No	ADA-17151A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	SOD2
Target Synonyms	GC1; IPOB; IPO-B; MNSOD; MVCD6; GClnc1; Mn-SOD; D2	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.05% proclin300, pH7.3.	Purification Method	Affinity purification
Positive Samples	U-2 OS	Application	ELISA, WB, IF/ICC, IHC-P

Cat.No

ADA-17151A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

SOD2

Target Synonyms

GC1; IPOB; IPO-B; MNSOD; MVCD6; GClnc1; Mn-SOD; D2

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.05% proclin300, pH7.3.

Purification Method

Affinity purification

Positive Samples

U-2 OS

Application

ELISA, WB, IF/ICC, IHC-P

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 25-222 of human SOD2 (NP_000627.2).	Target Species	Human
Immunogen Sequence	KHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVNNLNVTEEKYQEALAKGDVTAQIALQPALKFNGGGHINHSIFWTNLSPNGGGEPKGELLEAIKRDFGSFDKFKEKLTAASVGVQGSGWGWLGFNKERGHLQIAACPNQDPLQGTTGLIPLLGIDVWEHAYYLQYKNVRPDYLKAIWNVINWENVTERYMACKK	Uniprot ID	P04179

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 25-222 of human SOD2 (NP_000627.2).

Target Species

Human

Immunogen Sequence

KHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVNNLNVTEEKYQEALAKGDVTAQIALQPALKFNGGGHINHSIFWTNLSPNGGGEPKGELLEAIKRDFGSFDKFKEKLTAASVGVQGSGWGWLGFNKERGHLQIAACPNQDPLQGTTGLIPLLGIDVWEHAYYLQYKNVRPDYLKAIWNVINWENVTERYMACKK

Uniprot ID

P04179

Background Information

Uniprot Id

P04179
Target Species

Human
Target Name

SOD2
Target Full Name

Superoxide dismutase [Mn], mitochondrial
Target Function

Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
Target Involvement

Microvascular complications of diabetes 6 (MVCD6)
Target Subcellular Location

Mitochondrion matrix.
Target Protein Families

Iron/manganese superoxide dismutase family
Target Synonyms

Indophenoloxidase B; IPO B; IPOB; Manganese containing superoxide dismutase; Manganese SOD; Manganese superoxide dismutase; Mangano superoxide dismutase; Mn SOD; Mn superoxide dismutase; MNSOD; MVCD6; SOD 2; SOD2; SODM_HUMAN; Superoxide dismutase [Mn] mitochondrial; Superoxide dismutase [Mn], mitochondrial; Superoxide dismutase 2 mitochondrial
Target Background

This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1.

Rabbit anti-Human SOD2 Polyclonal Antibody

Specifications

Immunogen Information

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