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Recombinant Human Growth/differentiation factor 2 (GDF2)

ACP00137

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP00137 Target NameGDF2
Target SynonymsGDF-2;Bone morphogenetic protein 9;BMP-9FormLiquid or Lyophilized powder
Expression SystemE.coliExpression Range300-429aa
Mol Weight22.8 kDaProtein LengthFull Length of Mature Protein
PurityGreater than 90% as determined by SDS-PAGE.Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9UK05
Background Information
  • Uniprot Id

    Q9UK05

  • Target Species

    Human

  • Target Name

    GDF2

  • Target Full Name

    Growth/differentiation factor 2

  • Target Function

    Potent circulating inhibitor of angiogenesis. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG.

  • Target Involvement

    Telangiectasia, hereditary hemorrhagic, 5 (HHT5)

  • Target Subcellular Location

    Secreted.

  • Target Protein Families

    TGF-beta family

  • Target Tissue Specificity

    Detected in blood plasma (at protein level).

  • Target Research Area

    Cell Biology

  • Target Synonyms

    GDF2; BMP9Growth/differentiation factor 2; GDF-2; Bone morphogenetic protein 9; BMP-9

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