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Recombinant Human Neuron navigator 2 (NAV2), Truncated

ACP00532

Number
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Specifications


Cat.No ACP00532 Target NameNAV2
Target SynonymsHelicase APC down-regulated 1;Pore membrane and/or filament-interacting-like protein 2;Retinoic acid inducible in neuroblastoma 1;Steerin-2;Unc-53 homolog 2;unc53H2FormLiquid or Lyophilized powder
Expression SystemE.coliExpression Range950-1100aa
Mol Weight22.9 kDaProtein LengthPartial
PurityGreater than 85% as determined by SDS-PAGE.Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ8IVL1
Background Information
  • Uniprot Id

    Q8IVL1

  • Target Species

    Human

  • Target Name

    NAV2

  • Target Full Name

    Neuron navigator 2

  • Target Function

    Possesses 3' to 5' helicase activity and exonuclease activity. Involved in neuronal development, specifically in the development of different sensory organs.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    Nav/unc-53 family

  • Target Tissue Specificity

    Highly expressed in the brain, kidney and liver. Also expressed in the thyroid, mammary gland, spinal cord, heart, placenta and lung. Abundantly expressed in colon cancers.

  • Target Research Area

    Cancer

  • Target Synonyms

    NAV2; HELAD1; KIAA1419; POMFIL2; RAINB1; STEERIN2Neuron navigator 2; EC 3.6.4.12; Helicase APC down-regulated 1; Pore membrane and/or filament-interacting-like protein 2; Retinoic acid inducible in neuroblastoma 1; Steerin-2; Unc-53 homolog 2; unc53H2

  • Target Background

    This gene encodes a member of the neuron navigator gene family, which may play a role in cellular growth and migration. Multiple transcript variants encoding different isoforms have been found for this gene.

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