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| Cat.No | ACP00671 | Target Name | ACP5 |
|---|---|---|---|
| Target Synonyms | TR-AP;Tartrate-resistant acid ATPase;TrATPase;Type 5 acid phosphatase | Form | Liquid or Lyophilized powder |
| Expression System | Yeast | Expression Range | 22-325aa |
| Mol Weight | 35.8 kDa | Protein Length | Full Length of Mature Protein |
| Purity | Greater than 95% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P13686 |
|---|
Uniprot Id
P13686
Target Species
Human
Target Name
ACP5
Target Full Name
Tartrate-resistant acid phosphatase type 5
Target Function
Involved in osteopontin/bone sialoprotein dephosphorylation. Its expression seems to increase in certain pathological states such as Gaucher and Hodgkin diseases, the hairy cell, the B-cell, and the T-cell leukemias.
Target Involvement
Spondyloenchondrodysplasia with immune dysregulation (SPENCDI)
Target Subcellular Location
Lysosome.
Target Protein Families
Metallophosphoesterase superfamily, Purple acid phosphatase family
Target Research Area
Metabolism
Target Synonyms
ype 5 acid phosphatase; Acid phosphatase 5 tartrate resistant; Acid phosphatase 5; tartrate resistant; ACP5; EC 3.1.3.2; MGC117378; PPA5_HUMAN; serum band 5 tartrate-resistant acid phosphatase; SPENCDI; T5ap; Tartrate resistant acid ATPase; Tartrate resistant acid phosphatase type 5; Tartrate resistant acid phosphatase type 5 precursor; Tartrate-resistant acid ATPase; Tartrate-resistant acid phosphatase type 5; TR AP; TR-AP; TRACP 5; TRAP; TrATPase; Type 5 acid phosphatase
Target Background
This gene encodes an iron containing glycoprotein which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate.
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