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| Cat.No | ACP01022 | Target Name | LY86 |
|---|---|---|---|
| Form | Liquid or Lyophilized powder | Expression System | E.coli |
| Expression Range | 21-162aa | Mol Weight | 28.6 kDa |
| Protein Length | Full Length of Mature Protein | Purity | Greater than 90% as determined by SDS-PAGE. |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O95711 |
|---|
Uniprot Id
O95711
Target Species
Human
Target Name
LY86
Target Full Name
Lymphocyte antigen 86
Target Function
May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell surface expression.
Target Subcellular Location
Secreted, extracellular space. Note=Associated with CD180 at the cell surface.
Target Tissue Specificity
Highly expressed in B-cells, monocytes and tonsil.
Target Research Area
Immunology
Target Synonyms
BPAD; dJ80N2.1; Ly 86; Ly-86; Ly86; LY86_HUMAN; Lymphocyte antigen 86; Lymphocyte antigen 86 precursor; Major affective disorder 1; MD 1; MD-1; MD1 protein; MD1 RP105 associated ; MMD 1; MMD-1; Protein MD 1; Protein MD-1; RP1-80N2.1
Target Background
Acts upstream of or within positive regulation of lipopolysaccharide-mediated signaling pathway. Predicted to be located in extracellular space.
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