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Recombinant Human Galectin-3-binding protein (LGALS3BP)

ACP01156

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Specifications

Cat.No	ACP01156	Target Name	LGALS3BP
Target Synonyms	(Basement membrane autoantigen p105)(Lectin galactoside-binding soluble 3-binding protein)(Mac-2-binding protein)(MAC2BP)(Mac-2 BP)(Tumor-associated antigen 90K)	Form	Liquid or Lyophilized powder
Expression System	E.coli	Expression Range	19-585aa
Mol Weight	67.4 kDa	Protein Length	Full Length of Mature Protein
Purity	Greater than 85% as determined by SDS-PAGE.	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q08380

Background Information

Uniprot Id

Q08380
Target Species

Human
Target Name

LGALS3BP
Target Full Name

Galectin-3-binding protein
Target Function

Promotes integrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells.
Target Subcellular Location

Secreted. Secreted, extracellular space, extracellular matrix.
Target Tissue Specificity

Ubiquitous. Detected in body fluids such as semen, milk, serum, tears, saliva and urine. Expressed by keratinocytes and fibroblasts.
Target Research Area

Cancer
Target Synonyms

(Basement membrane autoantigen p105)(Lectin galactoside-binding soluble 3-binding protein)(Mac-2-binding protein)(MAC2BP)(Mac-2 BP)(Tumor-associated antigen 90K)
Target Background

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1.

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Recombinant Human Galectin-3-binding protein (LGALS3BP)

Specifications

Immunogen Information

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