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| Cat.No | ACP01278 | Target Name | H2BC12 |
|---|---|---|---|
| Form | Liquid or Lyophilized powder | Expression System | E.coli |
| Expression Range | 2-126aa | Mol Weight | 21.2 kDa |
| Protein Length | Full Length of Mature Protein | Purity | Greater than 85% as determined by SDS-PAGE. |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O60814 |
|---|
Uniprot Id
O60814
Target Species
Human
Target Name
H2BC12
Target Full Name
Histone H2B type 1-K
Target Function
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.; Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid.
Target Subcellular Location
Nucleus. Chromosome.
Target Protein Families
Histone H2B family
Target Research Area
Others
Target Synonyms
H2BC12; H2BFT; HIRIP1; HIST1H2BK; Histone H2B type 1-K; H2B K; HIRA-interacting protein 1
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