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Recombinant Human CHGB protein expression is initiated by transfecting e.coli cells with a DNA expression vector containing the gene encoding the protein of interest (328-677aa). The subsequent culturing of the cells induces the expression of the desired protein. The protein is equipped with a N-terminal 6xHis-GST tag. The resulting recombinant Human CHGB protein is collected and purified from the cell lysate through affinity purification, demonstrating a purity greater than 85%, as indicated by SDS-PAGE.
Recombinant Human CHGB protein expression is initiated by transfecting e.coli cells with a DNA expression vector containing the gene encoding the protein of interest (328-677aa). The subsequent culturing of the cells induces the expression of the desired protein. The protein is equipped with a N-terminal 6xHis-GST tag. The resulting recombinant Human CHGB protein is collected and purified from the cell lysate through affinity purification, demonstrating a purity greater than 85%, as indicated by SDS-PAGE.
| Cat.No | ACP01669 | Target Name | CHGB |
|---|---|---|---|
| Target Synonyms | (Chromogranin-B)(CgB)(Secretogranin I)(SgI) | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 328-677aa |
| Mol Weight | 73.5 kDa | Protein Length | Partial |
| Purity | Greater than 85% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P05060 |
|---|
Uniprot Id
P05060
Target Species
Human
Target Name
CHGB
Target Full Name
Secretogranin-1
Target Function
Secretogranin-1 is a neuroendocrine secretory granule protein, which may be the precursor for other biologically active peptides.
Target Subcellular Location
Secreted. Note=Neuroendocrine and endocrine secretory granules.
Target Protein Families
Chromogranin/secretogranin protein family
Target Tissue Specificity
Expressed in the adrenal medulla, and in pheochromocytoma. Not expressed in liver.
Target Research Area
Neuroscience
Target Synonyms
CCB peptide; Cg B; CgB; Chgb; Chromogranin-B; ChromograninB; SCG1; SCG1_HUMAN; Secretogranin 1; Secretogranin B; Secretogranin I; SgI
Target Background
This gene encodes a tyrosine-sulfated secretory protein abundant in peptidergic endocrine cells and neurons. This protein may serve as a precursor for regulatory peptides.
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