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| Cat.No | ACP01803 | Target Name | IARS |
|---|---|---|---|
| Target Synonyms | Isoleucyl-tRNA synthetase;IRS;IleRS | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 693-852aa |
| Mol Weight | 26.3 kDa | Protein Length | Partial |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P41252 |
|---|
Uniprot Id
P41252
Target Species
Human
Target Name
IARS1
Target Full Name
Isoleucine--tRNA ligase, cytoplasmic
Target Function
Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA.
Target Involvement
Growth retardation, intellectual developmental disorder, hypotonia, and hepatopathy (GRIDHH)
Target Subcellular Location
Cytoplasm. Cytoplasm, cytosol.
Target Protein Families
Class-I aminoacyl-tRNA synthetase family
Target Tissue Specificity
Expressed in liver and muscle (at protein level).
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
IARS1; IARS; Isoleucine--tRNA ligase; cytoplasmic; EC 6.1.1.5; Isoleucyl-tRNA synthetase; IRS; IleRS
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