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In the process of expressing the recombinant Human GPR84 protein, Yeast cells are transfected with a DNA expression vector that carries the gene encoding the desired protein (1-26aa). The cells are then cultured to induce the expression of the intended protein. The protein features a C-terminal hFc tag fusion. The recombinant Human GPR84 protein is collected and purified from the cell lysate through affinity purification, with its purity surpassing 85%, as assessed by SDS-PAGE.
In the process of expressing the recombinant Human GPR84 protein, Yeast cells are transfected with a DNA expression vector that carries the gene encoding the desired protein (1-26aa). The cells are then cultured to induce the expression of the intended protein. The protein features a C-terminal hFc tag fusion. The recombinant Human GPR84 protein is collected and purified from the cell lysate through affinity purification, with its purity surpassing 85%, as assessed by SDS-PAGE.
| Cat.No | ACP01855 | Target Name | GPR84 |
|---|---|---|---|
| Target Synonyms | GPR84; EX33; G-protein coupled receptor 84; Inflammation-related G-protein coupled receptor EX33 | Form | Liquid or Lyophilized powder |
| Expression System | Yeast | Expression Range | 1-26aa |
| Mol Weight | 31.2 kDa | Protein Length | Partial |
| Purity | Greater than 90% as determined by SDS-PAGE.Greater than 90% as determined by SEC-HPLC. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9NQS5 |
|---|
Uniprot Id
Q9NQS5
Target Species
Human
Target Name
GPR84
Target Full Name
G-protein coupled receptor 84
Target Function
Receptor for medium-chain free fatty acid (FFA) with carbon chain lengths of C9 to C14. Capric acid (C10:0), undecanoic acid (C11:0) and lauric acid (C12:0) are the most potent agonists. Not activated by short-chain and long-chain saturated and unsaturated FFAs. Activation by medium-chain free fatty acid is coupled to a pertussis toxin sensitive G(i/o) protein pathway. May have important roles in processes from fatty acid metabolism to regulation of the immune system.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
G-protein coupled receptor 1 family
Target Tissue Specificity
Expressed predominantly in hematopoietic tissues. High levels detected in the bone marrow and lower levels in the peripheral leukocytes and lung. Also expressed in brain, heart, muscle, colon, thymus, spleen, kidney, liver, placenta and intestine. Within
Target Research Area
Signal Transduction
Target Synonyms
GPR84; EX33; G-protein coupled receptor 84; Inflammation-related G-protein coupled receptor EX33
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