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Recombinant Human Interferon alpha-6 (IFNA6)

The region for expressing recombinant Human IFNA6 contains amino acids 21-189. The expected molecular weight for the IFNA6 protein is calculated to be 25.1 kDa. This protein is generated in a e.coli-based system. The IFNA6 gene fragment has been modified by fusing the N-terminal 10xHis tag and C-terminal Myc tag, providing convenience in detecting and purifying the recombinant IFNA6 protein during the following stages.Human interferon alpha-6 (IFNA6) belongs to the interferon alpha family, a group of cytokines crucial for the antiviral immune response. Produced by various immune cells, particularly leukocytes, IFNA6 plays a pivotal role in inhibiting viral replication and spread by inducing the expression of antiviral proteins within infected cells. Additionally, IFNA6 contributes to the activation of immune cells, enhancing the overall antiviral defense. Research on IFNA6 spans virology, immunology, and clinical medicine, exploring its potential therapeutic applications in treating viral infections, certain cancers, and autoimmune diseases. Understanding the molecular mechanisms of IFNA6 provides insights into the intricate interplay between the immune system and pathogens.

ACP02427

The region for expressing recombinant Human IFNA6 contains amino acids 21-189. The expected molecular weight for the IFNA6 protein is calculated to be 25.1 kDa. This protein is generated in a e.coli-based system. The IFNA6 gene fragment has been modified by fusing the N-terminal 10xHis tag and C-terminal Myc tag, providing convenience in detecting and purifying the recombinant IFNA6 protein during the following stages.Human interferon alpha-6 (IFNA6) belongs to the interferon alpha family, a group of cytokines crucial for the antiviral immune response. Produced by various immune cells, particularly leukocytes, IFNA6 plays a pivotal role in inhibiting viral replication and spread by inducing the expression of antiviral proteins within infected cells. Additionally, IFNA6 contributes to the activation of immune cells, enhancing the overall antiviral defense. Research on IFNA6 spans virology, immunology, and clinical medicine, exploring its potential therapeutic applications in treating viral infections, certain cancers, and autoimmune diseases. Understanding the molecular mechanisms of IFNA6 provides insights into the intricate interplay between the immune system and pathogens.

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Specifications


Cat.No ACP02427 Target NameIFNA6
Target SynonymsIFNA6Interferon alpha-6; IFN-alpha-6; Interferon alpha-54; Interferon alpha-K; LeIF KFormLiquid or Lyophilized powder
Expression SystemE.coliExpression Range21-189aa
Mol Weight25.1 kDaProtein LengthFull Length of Mature Protein
PurityGreater than 90% as determined by SDS-PAGE.Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP05013
Background Information
  • Uniprot Id

    P05013

  • Target Species

    Human

  • Target Name

    IFNA6

  • Target Full Name

    Interferon alpha-6

  • Target Function

    Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.

  • Target Subcellular Location

    Secreted.

  • Target Protein Families

    Alpha/beta interferon family

  • Target Research Area

    Cancer

  • Target Synonyms

    IFNA6Interferon alpha-6; IFN-alpha-6; Interferon alpha-54; Interferon alpha-K; LeIF K

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