Recombinant Human Alpha-enolase (ENO1)

Enhance your metabolic research with our high-quality Recombinant Human ENO1 protein. Alpha-enolase, encoded by the human ENO1 gene, is a critical enzyme in the glycolytic pathway that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate. This multifunctional protein also has roles in several cellular processes, such as cell growth, differentiation, and apoptosis, making it a valuable asset for metabolic research. Synthesized using baculovirus expression systems, our recombinant protein features the full-length mature 2-434aa region and is designed with an N-terminal MBP tag and a C-terminal 6xHis tag for efficient purification. With a purity greater than 85% as determined by SDS-PAGE, the Recombinant Human ENO1 protein is supplied as a lyophilized powder, ensuring optimal stability and performance in your experiments.

ACP02632

Enhance your metabolic research with our high-quality Recombinant Human ENO1 protein. Alpha-enolase, encoded by the human ENO1 gene, is a critical enzyme in the glycolytic pathway that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate. This multifunctional protein also has roles in several cellular processes, such as cell growth, differentiation, and apoptosis, making it a valuable asset for metabolic research.
Synthesized using baculovirus expression systems, our recombinant protein features the full-length mature 2-434aa region and is designed with an N-terminal MBP tag and a C-terminal 6xHis tag for efficient purification. With a purity greater than 85% as determined by SDS-PAGE, the Recombinant Human ENO1 protein is supplied as a lyophilized powder, ensuring optimal stability and performance in your experiments.

Number

Cat.No	ACP02632	Target Name	ENO1
Form	Liquid or Lyophilized powder	Expression System	Baculovirus
Expression Range	2-434aa	Mol Weight	91.0 kDa
Protein Length	Full Length of Mature Protein	Purity	Greater than 85% as determined by SDS-PAGE.
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP02632

Target Name

ENO1

Form

Liquid or Lyophilized powder

Expression System

Baculovirus

Expression Range

2-434aa

Mol Weight

91.0 kDa

Protein Length

Full Length of Mature Protein

Purity

Greater than 85% as determined by SDS-PAGE.

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	P06733

Background Information

Uniprot Id

P06733
Target Species

Human
Target Name

ENO1
Target Full Name

Alpha-enolase
Target Function

Glycolytic enzyme the catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate. In addition to glycolysis, involved in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production.; MBP1 binds to the myc promoter and acts as a transcriptional repressor. May be a tumor suppressor.
Target Subcellular Location

Cytoplasm. Cell membrane. Cytoplasm, myofibril, sarcomere, M line. Note=Can translocate to the plasma membrane in either the homodimeric (alpha/alpha) or heterodimeric (alpha/gamma) form. ENO1 is localized to the M line.; [Isoform MBP-1]: Nucleus.
Target Protein Families

Enolase family
Target Tissue Specificity

The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons.
Target Research Area

Metabolism
Target Synonyms

2 phospho D glycerate hydro lyase; 2-phospho-D-glycerate hydro-lyase; Alpha enolase; Alpha enolase like 1; Alpha-enolase; C myc promoter binding protein; C-myc promoter-binding protein; EC 4.2.1.11; eno1; ENO1L1; ENOA_HUMAN; Enolase 1 (alpha); Enolase 1 (alpha) like 1; Enolase 1; Enolase alpha; MBP 1; MBP-1; MBP1; MBPB1; MPB 1; MPB-1; MPB1; MYC promoter binding protein 1; NNE; Non neural enolase; Non-neural enolase; Phosphopyruvate hydratase; Plasminogen binding protein; Plasminogen-binding protein; PPH; Tau crystallin
Target Background

This gene encodes alpha-enolase, one of three enolase isoenzymes found in mammals. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a glycolytic enzyme. Alpha-enolase in addition, functions as a structural lens protein (tau-crystallin) in the monomeric form. Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor. Several pseudogenes have been identified, including one on the long arm of chromosome 1. Alpha-enolase has also been identified as an autoantigen in Hashimoto encephalopathy.

Recombinant Human Alpha-enolase (ENO1)

Specifications

Immunogen Information

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