Recombinant Human Microtubule-associated protein 1S (MAP1S), Truncated

Uniprot Id

Q66K74

Target Species

Human

Target Name

MAP1S

Target Full Name

Microtubule-associated protein 1S

Target Function

Microtubule-associated protein that mediates aggregation of mitochondria resulting in cell death and genomic destruction (MAGD). Plays a role in anchoring the microtubule organizing center to the centrosomes. Binds to DNA. Plays a role in apoptosis. Involved in the formation of microtubule bundles.

Target Subcellular Location

Nucleus. Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle.

Target Protein Families

MAP1 family

Target Tissue Specificity

Expressed in neurons (at protein level). Expressed in spermatocytes, spermatids and spermatozoa. Expressed in the cerebral cortex. Highly expressed in testis. Moderately expressed in the brain, colon, heart, kidney, liver, lung, placenta, small intestine,

Target Research Area

Apoptosis

Target Synonyms

BPY2-interacting protein 1; BPY2IP1; C19orf5; FLJ10669; MAP-1S; MAP1S; MAP1S light chain; MAP1S_HUMAN; MAP8; MGC133087; microtubule-associated protein 1S; Microtubule-associated protein 8; Variable charge Y chromosome 2-interacting protein 1; VCY2-interacting protein 1; VCY2IP-1; VCY2IP1

Target Background

Enables DNA binding activity and cytoskeletal protein binding activity. Involved in microtubule bundle formation; neuron projection morphogenesis; and regulation of chromatin disassembly. Located in several cellular components, including microtubule cytoskeleton; nuclear lumen; and perinuclear region of cytoplasm.