Recombinant Human Peptide YY protein (PYY), Truncated

The expression region of this recombinant Human PYY covers amino acids 31-64. This PYY protein is expected to have a theoretical molecular weight of 31.1 kDa. This PYY protein is produced using e.coli expression system. The PYY coding gene included the N-terminal GST tag, which simplifies the detection and purification processes of the recombinant PYY protein in following stages of expression and purification.Human peptide YY (PYY) is a peptide hormone that plays a crucial role in appetite regulation and energy homeostasis. Produced and released by enteroendocrine cells in the gastrointestinal tract, particularly in the ileum and colon, PYY is released in response to food intake. It functions as an appetite suppressant by signaling to the brain, where it binds to Y2 receptors in the hypothalamus. The main function of PYY is to reduce appetite, slow down gastric emptying, and inhibit pancreatic secretion, collectively contributing to the feeling of satiety and the regulation of energy balance. Research on PYY often focuses on its potential as a therapeutic target for obesity and metabolic disorders. Understanding its intricate role in appetite control provides valuable insights into the complex mechanisms of energy regulation in the human body.