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| Cat.No | ACP02907 | Target Name | PMP2 |
|---|---|---|---|
| Target Synonyms | FABP8; M FABP; MP2; Myelin FABP ; Myelin P2 protein; MYP2_HUMAN; P2; Peripheral myelin protein 2; PMP2 | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 1-132aa |
| Mol Weight | 41.9kDa | Protein Length | Full length |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P02689 |
|---|
Uniprot Id
P02689
Target Species
Human
Target Name
PMP2
Target Full Name
Myelin P2 protein
Target Function
May play a role in lipid transport protein in Schwann cells. May bind cholesterol.
Target Subcellular Location
Cytoplasm.
Target Protein Families
Calycin superfamily, Fatty-acid binding protein (FABP) family
Target Research Area
Transport
Target Synonyms
FABP8; M FABP; MP2; Myelin FABP ; Myelin P2 protein; MYP2_HUMAN; P2; Peripheral myelin protein 2; PMP2
Target Background
The protein encoded by this gene localizes to myelin sheaths of the peripheral nervous system. The encoded protein can bind both the membrane layers of the sheaths and monomeric lipids, and is thought to provide stability to the sheath. A defect in this gene was shown to be a cause of dominant demyelinating CMT neuropathy.
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