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| Cat.No | ACP03089 | Target Name | CALML5 |
|---|---|---|---|
| Target Synonyms | CALL5_HUMAN; CALML5; Calmodulin like 5; Calmodulin-like protein 5; Calmodulin-like skin protein; CLSP | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 2-146aa |
| Mol Weight | 31.8kDa | Protein Length | Full Length of Mature Protein |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9NZT1 |
|---|
Uniprot Id
Q9NZT1
Target Species
Human
Target Name
CALML5
Target Full Name
Calmodulin-like protein 5
Target Function
Binds calcium. May be involved in terminal differentiation of keratinocytes.
Target Tissue Specificity
Particularly abundant in the epidermis where its expression is directly related to keratinocyte differentiation. Very low expression in lung.
Target Research Area
Cell Biology
Target Synonyms
CALL5_HUMAN; CALML5; Calmodulin like 5; Calmodulin-like protein 5; Calmodulin-like skin protein; CLSP
Target Background
This gene encodes a novel calcium binding protein expressed in the epidermis and related to the calmodulin family of calcium binding proteins. Functional studies with recombinant protein demonstrate it does bind calcium and undergoes a conformational change when it does so. Abundant expression is detected only in reconstructed epidermis and is restricted to differentiating keratinocytes. In addition, it can associate with transglutaminase 3, shown to be a key enzyme in the terminal differentiation of keratinocytes.
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