Recombinant Human Fibroblast growth factor 13 (FGF13)

Cat.No	ACP03386	Target Name	FGF13
Target Synonyms	FGF 13; FGF 2; FGF-13; FGF13; FGF13_HUMAN; FGF2; FHF 2; FHF-2; FHF2; Fibroblast growth factor 13; Fibroblast growth factor homologous factor 2; OTTHUMP00000024143; OTTHUMP00000024144	Form	Liquid or Lyophilized powder
Expression System	E.coli	Expression Range	1-245aa
Mol Weight	31.6kDa	Protein Length	Full length
Purity	Greater than 90% as determined by SDS-PAGE.	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP03386

Target Name

FGF13

Target Synonyms

FGF 13; FGF 2; FGF-13; FGF13; FGF13_HUMAN; FGF2; FHF 2; FHF-2; FHF2; Fibroblast growth factor 13; Fibroblast growth factor homologous factor 2; OTTHUMP00000024143; OTTHUMP00000024144

Form

Liquid or Lyophilized powder

Expression System

E.coli

Expression Range

1-245aa

Mol Weight

31.6kDa

Protein Length

Full length

Purity

Greater than 90% as determined by SDS-PAGE.

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	Q92913

Background Information

Uniprot Id

Q92913
Target Species

Human
Target Name

FGF13
Target Full Name

Fibroblast growth factor 13
Target Function

Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. Through its action on microtubules, may participate in the refinement of axons by negatively regulating axonal and leading processes branching. Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus. May regulate voltage-gated sodium channels transport and function. May also play a role in MAPK signaling. Required for the development of axonal initial segment-targeting inhibitory GABAergic synapses made by chandelier neurons.
Target Subcellular Location

Cell projection, filopodium. Cell projection, growth cone. Cell projection, dendrite. Nucleus. Cytoplasm.; [Isoform 1]: Nucleus, nucleolus.; [Isoform 2]: Cytoplasm. Nucleus.
Target Protein Families

Heparin-binding growth factors family
Target Tissue Specificity

Ubiquitously expressed. Predominantly expressed in the nervous system.
Target Research Area

Signal Transduction
Target Synonyms

FGF 13; FGF 2; FGF-13; FGF13; FGF13_HUMAN; FGF2; FHF 2; FHF-2; FHF2; Fibroblast growth factor 13; Fibroblast growth factor homologous factor 2; OTTHUMP00000024143; OTTHUMP00000024144
Target Background

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This gene is located in a region on chromosome X, which is associated with Borjeson-Forssman-Lehmann syndrome (BFLS), making it a possible candidate gene for familial cases of the BFLS, and for other syndromal and nonspecific forms of X-linked cognitive disability mapping to this region. Alternative splicing of this gene at the 5' end results in several transcript variants encoding different isoforms with different N-termini.

Recombinant Human Fibroblast growth factor 13 (FGF13)

Specifications

Immunogen Information

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