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| Cat.No | ACP03489 | Target Name | TNNC2 |
|---|---|---|---|
| Target Synonyms | TNNC2; Troponin C; skeletal muscle | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 1-160aa |
| Mol Weight | 45.0kDa | Protein Length | Full length |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P02585 |
|---|
Uniprot Id
P02585
Target Species
Human
Target Name
TNNC2
Target Full Name
Troponin C, skeletal muscle
Target Function
Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments.
Target Protein Families
Troponin C family
Target Research Area
Signal Transduction
Target Synonyms
TNNC2; Troponin C; skeletal muscle
Target Background
Troponin (Tn), a key protein complex in the regulation of striated muscle contraction, is composed of 3 subunits. The Tn-I subunit inhibits actomyosin ATPase, the Tn-T subunit binds tropomyosin and Tn-C, while the Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. The protein encoded by this gene is the Tn-C subunit.
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