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| Cat.No | ACP03593 | Target Name | DCTD |
|---|---|---|---|
| Target Synonyms | dCMP deaminase; dctD; DCTD_HUMAN; Deoxycytidylate deaminase; MGC111062 | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 1-178aa |
| Mol Weight | 47.0kDa | Protein Length | Full Length of BC001286 |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P32321 |
|---|
Uniprot Id
P32321
Target Species
Human
Target Name
DCTD
Target Full Name
Deoxycytidylate deaminase
Target Function
Supplies the nucleotide substrate for thymidylate synthetase.
Target Protein Families
Cytidine and deoxycytidylate deaminase family
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
dCMP deaminase; dctD; DCTD_HUMAN; Deoxycytidylate deaminase; MGC111062
Target Background
The protein encoded by this gene catalyzes the deamination of dCMP to dUMP, the nucleotide substrate for thymidylate synthase. The encoded protein is allosterically activated by dCTP and inhibited by dTTP, and is found as a homohexamer. This protein uses zinc as a cofactor for its activity. Two transcript variants encoding different isoforms have been found for this gene.
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