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The expression region of this recombinant Human ACRV1 covers amino acids 22-265. The calculated molecular weight for this ACRV1 protein is 41.8 kDa. This protein is generated in a e.coli-based system. The N-terminal 6xHis-SUMO tag was fused into the coding gene segment of ACRV1, making it easier to detect and purify the ACRV1 recombinant protein in the later stages of expression and purification.Acrosomal protein SP-10 (ACRV1) is primarily associated with research in the field of male reproduction. One of its most crucial research directions involves its function in germ cell development and sperm maturation processes. SP-10 is a key protein during sperm maturation, present in the acrosome of sperm, a structure critical in the fertilization process. Researchers focus on understanding the exact functions of SP-10 in sperm formation, motility, and fertilization to gain insights into its contributions to reproductive health. SP-10 is linked to issues with male fertility, including difficulties in achieving pregnancy and lower fertility rates. This has attracted significant attention in the fields of reproductive medicine and andrology research.
The expression region of this recombinant Human ACRV1 covers amino acids 22-265. The calculated molecular weight for this ACRV1 protein is 41.8 kDa. This protein is generated in a e.coli-based system. The N-terminal 6xHis-SUMO tag was fused into the coding gene segment of ACRV1, making it easier to detect and purify the ACRV1 recombinant protein in the later stages of expression and purification.Acrosomal protein SP-10 (ACRV1) is primarily associated with research in the field of male reproduction. One of its most crucial research directions involves its function in germ cell development and sperm maturation processes. SP-10 is a key protein during sperm maturation, present in the acrosome of sperm, a structure critical in the fertilization process. Researchers focus on understanding the exact functions of SP-10 in sperm formation, motility, and fertilization to gain insights into its contributions to reproductive health. SP-10 is linked to issues with male fertility, including difficulties in achieving pregnancy and lower fertility rates. This has attracted significant attention in the fields of reproductive medicine and andrology research.
| Cat.No | ACP04055 | Target Name | ACRV1 |
|---|---|---|---|
| Target Synonyms | Acrosomal protein SP 10; Acrosomal protein SP-10; Acrosomal vesicle protein 1; ACRV1; ASPX_HUMAN; D11S4365; Msa63; SP 10; Sp10; SPACA2; Sperm protein 10 | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 22-265aa |
| Mol Weight | 41.8kDa | Protein Length | Full Length of Mature Protein |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P26436 |
|---|
Uniprot Id
P26436
Target Species
Human
Target Name
ACRV1
Target Full Name
Acrosomal protein SP-10
Target Subcellular Location
Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Nascent acrosomal vesicle of Golgi phase spermatids.
Target Tissue Specificity
Testis.
Target Research Area
Signal Transduction
Target Synonyms
Acrosomal protein SP 10; Acrosomal protein SP-10; Acrosomal vesicle protein 1; ACRV1; ASPX_HUMAN; D11S4365; Msa63; SP 10; Sp10; SPACA2; Sperm protein 10
Target Background
This gene encodes a testis-specific, differentiation antigen, acrosomal vesicle protein 1, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the acrosomal membranes and matrix of mature sperm. The acrosomal vesicle protein 1 may be involved in sperm-zona binding or penetration. Alternatively spliced transcript variants have been described.
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