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| Cat.No | ACP04068 | Target Name | CLVS2 |
|---|---|---|---|
| Target Synonyms | bA160A10.4; C6orf212; C6orf213; Clavesin-2; clvs2; CLVS2_HUMAN; Retinaldehyde-binding protein 1-like 2; RLBP1L2 | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 1-327aa |
| Mol Weight | 54.0kDa | Protein Length | Full length |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q5SYC1 |
|---|
Uniprot Id
Q5SYC1
Target Species
Human
Target Name
CLVS2
Target Full Name
Clavesin-2
Target Function
Required for normal morphology of late endosomes and/or lysosomes in neurons. Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).
Target Subcellular Location
Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle. Early endosome membrane; Peripheral membrane protein.
Target Research Area
Signal Transduction
Target Synonyms
bA160A10.4; C6orf212; C6orf213; Clavesin-2; clvs2; CLVS2_HUMAN; Retinaldehyde-binding protein 1-like 2; RLBP1L2
Target Background
This gene encodes a protein that belongs to the SEC14/CRAL-TRIO family of proteins. A similar protein in rat is thought to function in the endosomal pathway between early endosomes and mature lysosomes.
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