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| Cat.No | ACP04137 | Target Name | THAP12 |
|---|---|---|---|
| Form | Liquid or Lyophilized powder | Expression System | E.coli |
| Expression Range | 612-761aa | Mol Weight | 33.6kDa |
| Protein Length | Partial | Purity | Greater than 90% as determined by SDS-PAGE. |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O43422 |
|---|
Uniprot Id
O43422
Target Species
Human
Target Name
THAP12
Target Full Name
52 kDa repressor of the inhibitor of the protein kinase
Target Function
Upstream regulator of interferon-induced serine/threonine protein kinase R (PKR). May block the PKR-inhibitory function of DNAJC3, resulting in restoration of kinase activity and suppression of cell growth.
Target Research Area
Signal Transduction
Target Synonyms
THAP12; DAP4; P52RIPK; PRKRIR; THAP0; 52 kDa repressor of the inhibitor of the protein kinase; p52rIPK; 58 kDa interferon-induced protein kinase-interacting protein; p58IPK-interacting protein; Death-associated protein 4; THAP domain-containing protein 0; THAP domain-containing protein 12
Target Background
Predicted to enable DNA binding activity; metal ion binding activity; and protein dimerization activity. Predicted to be involved in negative regulation of cell population proliferation and signal transduction. Predicted to be located in nucleus.
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