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| Cat.No | ACP04576 | Target Name | BANK1 |
|---|---|---|---|
| Target Synonyms | BANK1B-cell scaffold protein with ankyrin repeats | Form | Liquid or Lyophilized powder |
| Expression System | Yeast | Expression Range | 1-785aa |
| Mol Weight | 91.3kDa | Protein Length | Full length |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8NDB2 |
|---|
Uniprot Id
Q8NDB2
Target Species
Human
Target Name
BANK1
Target Full Name
B-cell scaffold protein with ankyrin repeats
Target Function
Involved in B-cell receptor (BCR)-induced Ca(2+) mobilization from intracellular stores. Promotes Lyn-mediated phosphorylation of IP3 receptors 1 and 2.
Target Involvement
Systemic lupus erythematosus (SLE)
Target Tissue Specificity
Expressed in B-cell but not T-cell or myeloid cell lines. Highest expression in CD19(+) B-cells, with very low expression in other cell populations.
Target Research Area
Immunology
Target Synonyms
BANK1B-cell scaffold protein with ankyrin repeats
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