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| Cat.No | ACP05623 | Target Name | HCN2 |
|---|---|---|---|
| Target Synonyms | BCNG-2; BCNG2 ; Brain cyclic nucleotide gated channel 2; Brain cyclic nucleotide-gated channel 2; HAC1; Hcn2; HCN2_HUMAN; Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9UL51 |
|---|
Uniprot Id
Q9UL51
Target Species
Human
Target Name
HCN2
Target Full Name
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
Target Function
Hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. Contributes to the native pacemaker currents in heart (If) and in neurons (Ih). Can also transport ammonium in the distal nephron. Produces a large instantaneous current. Modulated by intracellular chloride ions and pH; acidic pH shifts the activation to more negative voltages.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
Potassium channel HCN family
Target Tissue Specificity
Highly expressed throughout the brain. Detected at low levels in heart.
Target Synonyms
BCNG-2; BCNG2 ; Brain cyclic nucleotide gated channel 2; Brain cyclic nucleotide-gated channel 2; HAC1; Hcn2; HCN2_HUMAN; Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
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