Recombinant Human Solute carrier family 13 member 5 (SLC13A5), Truncated

Cat.No	ACP06026	Target Name	SLC13A5
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Protein Length	Partial	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP06026

Target Name

SLC13A5

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Protein Length

Partial

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	Q86YT5

Background Information

Uniprot Id

Q86YT5
Target Species

Human
Target Name

SLC13A5
Target Full Name

Na(+)/citrate cotransporter
Target Function

High-affinity sodium/citrate cotransporter that mediates citrate entry into cells. Transports citrate in a Na(+)-dependent manner, transport process is electrogenic and recognizes the trivalent form of citrate rather than the divalent form. Although citrate is its main substrate, other intermediates of the citric acid cycle, such as succinate, fumarate, malate, oxaloacetate and alpha-ketoglutarate can serve as substrates but with a much lower affinity compared to citrate. Shows a substrate sensitivity in the order of citrate > malate ~ alpha-ketoglutarate > succinate ~ fumarate > oxaloacetate ~ isocitrate. Shows substantial citrate transporter activity when sodium ions are replaced by either potassium or choline ions. Transport activity is potentiated by lithium ions in the presence of low concentrations of citrate but is inhibited by lithium ions in the presence of high concentrations of citrate. Involved in the regulation of citrate levels in the brain.
Target Involvement

Epileptic encephalopathy, early infantile, 25 (EIEE25)
Target Subcellular Location

Cell membrane; Multi-pass membrane protein.
Target Protein Families

SLC13A/DASS transporter (TC 2.A.47) family, NADC subfamily
Target Tissue Specificity

Expressed most predominantly in the liver, with moderate expression detectable in the brain and testis.
Target Synonyms

Na(+)/citrate cotransporter; NaC2/NaCT; NaCT; Novel solute carrier family 13 (sodium dependent dicarboxylate transporter) (Slc13a2 or 3) member; S13A5_HUMAN; Slc13a5; Sodium coupled citrate transporter; Sodium-coupled citrate transporter; Sodium-dependent citrate transporter; Solute carrier family 13 (sodium dependent citrate transporter); member 5; Solute carrier family 13 member 5

Recombinant Human Solute carrier family 13 member 5 (SLC13A5), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Solute carrier family 13 member 5 (SLC13A5), Truncated Now

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