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| Cat.No | ACP06869 | Target Name | CYB5A |
|---|---|---|---|
| Target Synonyms | CYB5A; CYB5; Cytochrome b5; Microsomal cytochrome b5 type A; MCB5 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P00167 |
|---|
Uniprot Id
P00167
Target Species
Human
Target Name
CYB5A
Target Full Name
Cytochrome b5
Target Function
Cytochrome b5 is a membrane-bound hemoprotein functioning as an electron carrier for several membrane-bound oxygenases.
Target Involvement
Methemoglobinemia CYB5A-related (METHB-CYB5A)
Target Subcellular Location
[Isoform 1]: Endoplasmic reticulum membrane; Single-pass membrane protein; Cytoplasmic side. Microsome membrane; Single-pass membrane protein; Cytoplasmic side.; [Isoform 2]: Cytoplasm.
Target Protein Families
Cytochrome b5 family
Target Synonyms
CYB5A; CYB5; Cytochrome b5; Microsomal cytochrome b5 type A; MCB5
Target Background
The protein encoded by this gene is a membrane-bound cytochrome that reduces ferric hemoglobin (methemoglobin) to ferrous hemoglobin, which is required for stearyl-CoA-desaturase activity. Defects in this gene are a cause of type IV hereditary methemoglobinemia. Three transcript variants encoding different isoforms have been found for this gene.
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