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| Cat.No | ACP07904 | Target Name | SMIM37 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8NCU8 |
|---|
Uniprot Id
Q8NCU8
Target Species
Human
Target Name
MTLN
Target Full Name
Mitoregulin
Target Function
Positively regulates mitochondrial complex assembly and/or stability. Increases mitochondrial membrane potential while decreasing mitochondrial reactive oxygen species. Increases mitochondrial respiration rate. Increased mitochondrial respiratory activity promotes myogenic differentiation which facilitates muscle growth and regeneration. Increases mitochondrial calcium retention capacity. Plays a role in maintenance of cellular lipid composition through its interaction with cytochrome b5 reductase CYB5R3 which is required for mitochondrial respiratory complex I activity. Interacts with the mitochondrial trifunctional enzyme complex (MTE) and enhances fatty acid beta-oxidation. Not required for MTE formation or stability. Modulates triglyceride clearance in adipocytes through its role in regulating fatty acid beta-oxidation and lipolysis
Target Subcellular Location
Mitochondrion inner membrane; Single-pass membrane protein.
Target Synonyms
MTLN; LEMP; LINC00116; MOXI; MPM; NCRNA00116; SMIM37; Mitoregulin; Micropeptide in mitochondria; Micropeptide regulator of beta-oxidation; Small integral membrane protein 37; lncRNA-encoded micropeptide
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