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| Cat.No | ACP08158 | Target Name | GRAMD4 |
|---|---|---|---|
| Target Synonyms | GRAMD4; DIP; KIAA0767; GRAM domain-containing protein 4; Death-inducing protein | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6IC98 |
|---|
Uniprot Id
Q6IC98
Target Species
Human
Target Name
GRAMD4
Target Full Name
GRAM domain-containing protein 4
Target Function
Plays a role as a mediator of E2F1-induced apoptosis in the absence of p53/TP53. Plays a role as a mediator of E2F1-induced apoptosis in the absence of p53/TP53. Inhibits TLR9 response to nucelic acids and regulates TLR9-mediated innate immune response.
Target Subcellular Location
Mitochondrion membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Target Tissue Specificity
Expressed in lung and in primary lung squamous cell carcinoma (LSCC).
Target Synonyms
GRAMD4; DIP; KIAA0767; GRAM domain-containing protein 4; Death-inducing protein
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